What You Should Know About Kratom

While kratom is not categorized as an opioid, like heroin and morphine, it can produce opioid-like effects in users, such as relaxation and pain relief. The leaves contain two major psychoactive ingredients, mitragynine and 7-hydroxymitragynine (7-OH), that attach to the same parts of the brain as opioids, called mu-opioid receptors. However, kratom is what’s known…

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Your Delivery Robot Is Here

Aarian Marshall: Hello. Michael Calore: Given today’s topic, I’m curious to know what is the most unexpected thing you’ve both ordered through a delivery app? Louise Matsakis: So I was on a press trip to China recently, and I was taking notes during an interview, and I got pen all over my white pants. So…

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Sam Altman Says the GPT-5 Haters Got It All Wrong

OpenAI’s August launch of its GPT-5 large language model was somewhat of a disaster. There were glitches during the livestream, with the model generating charts with obviously inaccurate numbers. In a Reddit AMA with OpenAI employees, users complained that the new model wasn’t friendly, and called for the company to restore the previous version. Most…

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